Immune checkpoint inhibitors (ICIs) have transformed the field of oncology across numerous tumor types over the last 10 to 15 years. Historically administered intravenously, ICIs may cause infusion-related reactions, require line access, and pose substantial staff and chair-time burdens. Recently, 2 ICIs (atezolizumab and nivolumab) were approved for subcutaneous administration, with additional ICIs in development. In this paired conversation activity, community oncologist Lucio Gordan, MD, and academic oncologist Saby George, MD, discuss the real-world burden related to ICI therapies administered intravenously and how subcutaneous formulations address these burdens. They also compare the clinical efficacy and safety profiles of subcutaneous and intravenous ICI products. The activity also highlights the importance and role of the interprofessional, multidisciplinary team in shared decision-making, treatment individualization, operationalization of subcutaneous ICIs, and workflow optimization.
This content is also available as a podcast. You may listen here.
Course Credit:
1.00 ACPE Contact Hour
1.00 AMA PRA Category 1 CreditTM
1.00 ANCC Contact Hour
1.00 CA-BRN Contact Hour
1.00 Pharmacology Hour
Dates:
Opens: 2025-07-31
Closes: 2026-07-31
Target Audience:
This activity is intended for a national audience of community-based and hospital-based oncologists, urologists, dermatologists, surgical oncologists, thoracic surgeons, NPs, PAs, nurses, pharmacists.
This activity is supported by an educational grant from Merck Sharp & Dohme LLC.
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Christopher Flores, MD
Family Medicine Physician
Eisenhower Medical Center
Rancho Mirage, California -
Saby George, MD
Professor of Medicine
Roswell Park Comprehensive Cancer Center
Director of Network Clinical Trails
Roswell Park Comprehensive Cancer Center
Tenured Professor of Medicine
Jacobs School of Medicine
University of Buffalo
Buffalo, New York -
Lucio Gordan, MD
President and Managing Physician
Florida Cancer Specialists & Research Institute
Gainesville, Florida -
LaTosha Mollette, DNP
Family Nurse Practitioner
Louisiana Family Medicine Clinic
Jonesboro, Louisiana -
Michael Smith, PharmD
Clinical Pharmacist in Pain/Palliative Care
University of Michigan
Ann Arbor, Michigan